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KMID : 1094020060230030344
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Journal of Veterinary Clinics
2006 Volume.23 No. 3 p.344 ~ p.348
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Trial of Mycophenolate Mofetil Treatment on Necrotizing Meningoencephalitis in a Yorkshire Terrier Dog
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Jeon Hyo-Won
Kim Ha-Jung
Kim Ju-Won
Lim Chae-Young
Ko Ki-Jin
Cho Sue-Kyung
Gu Su-Hyun
Heo Ra-Young
Park Hyo-Jin
Park Chul
Jung Dong-In
Kang Byeong-Teck
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Abstract
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A 5-year-old, male Yorkshire terrier dog was presented with progressive seizure and anorexia. Definitive diagnosis of necrotizing meningoencephalitis(NME) was made based on characteristic clinical features, brain lesion with MRI, and histopathologic examination. The dog was treated with prednisolone for 20 days, firstly. Prednisolone and mycophenolate mofetil(MMF) were then administered for 40 days following the initial therapy. However, the clinical signs were not improved and seizure frequency was increased. This patient survived around 2 months after diagnosis. This case report described the clinical findings, imaging characteristics and pathologic features of NME in a Yorkshire terrier with trial treatment using MMF.
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KEYWORD
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necrotizing meningoencephalitis, seizure, mycophenolate mofetil
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